On Gastric and Duodenal Secretions
نویسندگان
چکیده
a polyamine-formaldehyde resin (Amberlite IR-4) as an anion exchange resin on the gastric secretions of rats. The acid neutralizing characteristics of the resin suggested its trial in the treatment of peptic ulcer but the large volume required to remove clinical amounts of acid from solution rendered its use impractical, even though feeding experiments showed the substance to be innocuous. However, in 1946 Martin and Wilkinson (3) overcame this difficulty. They showed that Amberlite IR-4 was an effective acid neutralizer in amounts practical for clinical use if a fine mesh
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